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The Role of Cannula Diameter in Improved Adipocyte Viability: A Quantitative Analysis

Zafer Özsoy MD, Zekeria Kul MD, Ayhan Bilir MD
DOI: http://dx.doi.org/10.1016/j.asj.2006.04.003 287-289 First published online: 1 May 2006


Background: Fat injection for soft tissue augmentation is a common procedure in plastic surgery. Because the limitation of fat injection is its resorption, understanding how different handling techniques affect adipocyte survival is crucial to optimizing long-term results.

Objective: In this study; we sought to determine the effect of aspiration and injection cannula diameters on adipocyte viability.

Methods: Fat aspiration samples were obtained from 6 female patients undergoing abdominoplasty. Viable adipocytes were counted at fat suspension, which was obtained with 2-, 3-, and 4-mm–diameter aspiration cannulas and injected with 1.6-, 2-, and 2.5-mm–diameter injection cannulas.

Results: A greater number of viable adipocytes were detected using a 4-mm–diameter aspiration cannula (419 × 104 cell/1 mL, P < .05) and a 2.5-mm–diameter injection cannula (410 × 104 cell/1 mL, P < .05).

Conclusions: The use of wider-diameter cannulas can potentially improve fat graft survival and reduce fat graft resorption.

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